why is everyone taking glp 1 GLP-1s have been dominating the headlines recently. For me, the change these medicines are having on nutrition, public health and how we treat metabolic medicine something I've spent years teaching, researching GLP-1 Drugs: Why Not Everyone

doi: 10.1016/j.neuroscience.2016.05.017 62 MiuraK.OshimaT.ItoC.HorikawaT.YamadaM.TomitaT.et al

This raised questions about whether GLP-1RAs could cause pancreatic effects beyond pancreatitis, including the development of PDAC

Eating quickly puts those on GLP-1s at risk overeating and then suffering with consequences

When the FDA removed tirzepatide in December 2024 and semaglutide in February 2025, they didnt just update a websitethey triggered a legal shutdown of the primary revenue stream for hundreds of facilities

Based on Obesity Canada guidelines and clinical trials (typically over ~1 year): Saxenda: ~58% total body weight loss Wegovy: ~1015% total body weight loss Tirzepatide: ~1520% (or more) total body weight loss weight loss is gradual and occurs over several months, with the most significant changes seen after reaching the full therapeutic dose results vary depending on adherence, lifestyle factors, and individual response 7

Low blood pressure: If your baseline blood pressure is already low, the combination may lead to frequent fainting or extreme dizziness